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闫凤侠(护理学院)

发布者:管理员       发布时间:2019/03/07

姓  名

闫凤侠

性  别

闫凤侠.jpg

出生年月

1982.08

     


科  别

护理学院

职  称

中级

最高学历

博士

     

讲师

最高学位

博士研究生

毕业院校

中山大学

导师(打√)

 

     

护理学

应诊时间:


出诊科室


联系电话:

15626209898

电子邮箱:

yanfengxia0807@163.com

个人简介(包括主要的学习工作经历、医疗专长、教学情况等)

 

20166月中山大学药学院博士毕业,毕业后继续在中山大学第一附属医院从事博士后相关研究工作,博士和博士后期间主要研究心脑血管相关疾病的病因和发病机制,并探讨该类疾病新的治疗靶点。现已发表SCI论文15篇,总计影响因子61.8分。博士后出站后于201711月到暨南大学护理学院从事教学和科研的相关工作,目前主要担任《社区护理》、《临床药理》和《外科护理学》课程的主讲工作。

 

社会任职

 

现任广东省护理学会护理信息专业委员会主委

 

研究方向(临床、课题)

 

临床护理、护理药理和慢性病的延续护理

 

 

 

 

荣誉与奖励

 

 

 

 

 

学术论著(近年发表的主要论文,专著请写明专著书名)

(1) Rifang Liao#*, Fengxia Yan#, Zhuanping Zeng#, Haitao Wang, Kaifeng Qiu, Jinying XuaWenhua Zheng*, Insulin-like growth factor-1 activates PI3K/Akt signalling to protect human retinal pigment epithelial cells from amiodarone-induced oxidative injury, Br J Pharmacol, 2018 Jan;175(1):125-139. (并列第一作者,IF=6.58)

(2) Yizhou Jiang#, Fengxia Yan#, Zhongping Feng, Philip Lazarovici, Wenhua Zheng*,Signaling Network of Forkhead Family of Transcription Factors (FOXO) in Dietary RestrictionCells, 2019 Dec 31;9(1). DOI: 10.3390/cells9010100, [Epub ahead of print]( 并列第一作者, IF=5.66)

(3) Fengxia Yan#, HuaMing Li#, ShangXuan Li#, ShiHui He, WeiPing Dai, Yan Li, Tian Tian Wang, MaoMao Shi, HaoXiang Yuan, Zhe Xu, JiaGuo Zhou, DaSheng Ning, ZhiWei Mo, ZhiJun Ou*, JingSong Ou*, The oxidized phospholipid POVPC impairs endothelial function and vasodilation via uncoupling endothelial nitric oxide synthase, J Mol Cell Cardiol, 2017 Nov;112:40-48. (第一作者,IF=5.3

(4) Rifang Liao#, Fengxia Yan#, Zhuanping Zeng#, Mohd Farhan, Peter Little, Remi Quirion, Lalit K. Srivastava, Wenhua Zheng*, Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway, Mol Neurobiol, (2017) 54:6931–6943. (并列第一作者,IF=4.58).

(5) Fengxia Yan#, Rifang Liao#, Marta Silva#, Shuai Li#, Yizhou Jiang, Tangming Peng, Philip Lazarovici,  Wenhua*,ZhengPristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway. J Cell Mol Med. 2020 Apr 29. doi: 10.1111/jcmm.15249. [Epub ahead of print]( (第一作者,IF=4.66).

(6) Fengxia Yan#, HaiTao Wang#, Yang Gao, Jiang Ping Xu, and Wenhua Zheng*, Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage, ACS Chem Neurosci, 2017 Aug 16;8(8):1713-1723. (第一作者,IF=3.86)

(7) Xiaoying  Zhang#Lifang Wang #, Lizhi Peng#Xiaoying Tian, Xiaoyuan Qiu, Huan Cao, Qiaohong Yang*,Rifang Liao* and Fengxia Yan*Dihydromyricetin protects HUVECs of oxidative damage induced by sodium nitroprusside through activating PI3K/Akt/FoxO3a signalling pathwayJ Cell Mol Med. 2019 May 21 doi: 10.1111/jcmm.14406[Epub ahead of print].(通讯作者,IF=4.66

(8) Fengxia Yan#, Zilong Gao, Pin Chen, Li Huang, Dangui Wang, Na Chen, Ruixiang Wu, Jing Feng, Shan Cui, Wei Lu, JinHui Wang*, Coordinated Plasticity between Barrel Cortical Glutamatergic and GABAergic Neurons during Associative Memory. Neural Plast, 2016 Dec 14. doi: 10.1155/2016/5648390[Epub ahead of print]. (第一作者,IF=3.59

(9) Fengxia Yan #, Rifang Liao#, Mohd Farhan, Tinghuai Wang, Jiashu Chen, Zhong Wang, Peter J. Little, Wenhua Zheng*, Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells, Biomedicine & Pharmacotherapy, 2016, 84(12): 1538–1550. (第一作者,IF=3.74)

(10) Rikang Wang#, Fengxia Yan #, Rifang Liao#, Pei Wan, Peter J.Little , Wenhua Zheng*, Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo, Mol Cell Endocrinol, 2017 May 15;447:71-78. (并列第一作者,IF=3.69

(11) Fengxia Yan#, Rifang Liao#, Peter J. Little, Wenhua Zheng*, Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl2like protein 11 and cyclindependent kinase inhibitor 1B, Molecula Medicine Reports. 2018 Feb;17. doi: 10.3892/mmr.2017.8215, [Epub ahead of print].第一作者,IF=1.85)

(12) Wenhua Zheng*, Qian Meng, Haitao Wang, Fengxia Yan, Peter J. Little, Xinguo Deng, Shaofen Lin, IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway, Mol Neurobiol (2018) 55:1915–1927.(第四作者,IF=4.58)

(13) Shuai Li#Shubhash Chandra chaudhary#, Xia Zhao#, Uma GaurJiankang Fang, Fengxia Yan and Wenhua Zheng*Artemisinin Protects Human Retinal Pigmented Epithelial Cells Against Hydrogen Peroxide-induced Oxidative Damage by Enhancing the Activation of AMP-active Protein Kinase, International Journal of Biological Sciences, 2019;15:2016-2028.(第六作者,IF=4.06)

(14) Haitao Wang#, Sufei Liao#, Ruojun Geng, Yongxin Zheng, Rifang Liao, Fengxia Yan, Thilini Thrimawithana, Peter J. Little, Zhongping Feng, Philip Lazarovici, Wenhua Zheng*, IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult, Journal of Molecular Neuroscience, 2015, 55(4):931-40. (第六作者,IF=2.57)

(15) Liu Linlin#, Zhiwen Zeng, Uma Gaur, Fengxia Yan and Wenhua Zheng*The p38-MAPK Pathway Is Involved in Neuroprotection of Artemisinin against H2O2-induced Apoptosis in PC12 CellsJournal of Pharmacy and Pharmacology7 (2017) 416-423第四作者,IF=2.39).

科研项目

(1) FoxO3aeNOS表达的调控在趋炎HDL介导血管舒张功能受损中的作用及机制研究,广州市基础与应用基础研究项目,主持,20

(2) FoxO1转录因子对神经肽W表达的调控在抑郁症形成中的作用及机制研究,广东省自然科学基金面上项目,主持10

(3) 青蒿素对H2O2诱导视网膜色素上皮细胞凋亡的保护作用及机制研究,暨南大学护理学院培育项目,主持,3

(4) 青蒿素对氧化损伤视网膜色素上皮细胞的保护作用及机制的研究,广东省中药局项目,主持,1

Fox03a 转录因子在葡萄膜黑色素痛中的作用及调节机制研究,广东省医学科研基金立项课题,主持,0.5



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